Opportunity Information: Apply for GLOBALHEALTHBAA MICROBICIDES 2021
The Microbicide 2020 R&D Project opportunity is a USAID-led funding call under the Global Health Broad Agency Announcement (BAA) focused on accelerating the research and development of new HIV prevention products designed for women. The central idea is to build partnerships that can move promising prevention technologies forward by combining scientific expertise, product development know-how, and real-world implementation experience. USAID is looking for collaborations that can co-create and co-design solutions, and where appropriate, co-invest alongside USAID, with the goal of producing practical, cost-effective tools that can meaningfully reduce HIV infections in settings with the highest burden.
A major emphasis of this addendum is women-centered choice in HIV prevention, especially for adolescent girls and young women in sub-Saharan Africa, where HIV incidence remains disproportionately high. The opportunity is meant to support the pipeline from early research through development and testing, including piloting, evaluation, and preparation for broader scale-up. In practice, that means proposals may span activities like advancing candidate microbicides or other female-controlled prevention modalities, improving delivery mechanisms, strengthening evidence through studies and trials, and addressing barriers that affect uptake and sustained use. USAID signals that it is not only interested in lab breakthroughs, but also in solutions that can realistically be manufactured, delivered, and used in resource-limited contexts.
This opportunity falls under a discretionary funding category and is listed as an “Other” funding instrument type, reflecting the flexible, partnership-oriented nature of the BAA approach. The activity area is science and technology and other research and development (CFDA 98.001). Rather than treating applicants as standard vendors, the framing encourages joint problem-solving and collaboration across sectors, including public health implementers, product developers, researchers, and private-sector partners who can help translate innovation into accessible prevention options.
Eligibility is broad and includes a wide range of potential applicants: county and local governments, city or township governments, independent school districts, federally recognized Native American tribal governments and other tribal organizations, nonprofits with or without 501(c)(3) status (excluding institutions of higher education in those specific categories), individuals, and for-profit organizations other than small businesses. This wide eligibility reflects USAID’s intent to attract unconventional teams and mixed partnerships, not just traditional academic or large institutional applicants.
Key administrative details include the funding opportunity number “GLOBALHEALTHBAA MICROBICIDES 2021,” with a listed original closing date of March 11, 2021, and a creation date of January 25, 2021. The stated award ceiling is up to $125,000,000, indicating the potential for large-scale support depending on the scope and structure of the proposed collaboration. Overall, the grant opportunity is designed to speed the development and eventual rollout of innovative HIV prevention products that women can control and choose, with a clear focus on impact in the regions and populations most affected.Apply for GLOBALHEALTHBAA MICROBICIDES 2021
- The Agency for International Development in the science and technology and other research and development sector is offering a public funding opportunity titled "The Microbicide 2020 R&D Project: Advancing the Research and Development of Innovative HIV Prevention Products for Women" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 98.001.
- This funding opportunity was created on 2021-01-25.
- Applicants must submit their applications by 2021-03-11. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $125,000,000.00 in funding.
- Eligible applicants include: County governments, City or township governments, Independent school districts, Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Individuals, For-profit organizations other than small businesses.
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Frequently Asked Questions (FAQs): Microbicide 2020 R&D Project (USAID Global Health BAA)
What is the Microbicide 2020 R&D Project opportunity?
The Microbicide 2020 R&D Project opportunity is a USAID-led funding call issued under the Global Health Broad Agency Announcement (BAA). It focuses on accelerating research and development of new HIV prevention products designed for women, with an emphasis on moving promising prevention technologies from research into development, testing, and readiness for broader rollout.
What is the main goal of this funding call?
The core goal is to speed the development and eventual availability of practical, cost-effective HIV prevention tools that women can control and choose. USAID is looking for partnerships that can combine scientific expertise, product development capabilities, and real-world implementation experience to reduce HIV infections, especially in settings with the highest burden.
What populations and regions are prioritized?
The opportunity highlights women-centered choice in HIV prevention, with special emphasis on adolescent girls and young women in sub-Saharan Africa, where HIV incidence remains disproportionately high.
What kinds of projects or activities may be supported?
Projects may span a pipeline from early research through development and testing. Based on the opportunity description, this can include advancing candidate microbicides or other female-controlled prevention modalities, improving delivery mechanisms, strengthening evidence through studies and trials, piloting and evaluation, and preparing for broader scale-up.
Is the opportunity limited to laboratory research?
No. USAID indicates it is interested not only in lab breakthroughs but also in solutions that can realistically be manufactured, delivered, and used in resource-limited contexts. That includes work that addresses barriers affecting uptake and sustained use.
What does USAID mean by partnerships and collaboration in this call?
The call is framed around collaboration and joint problem-solving rather than a standard vendor relationship. USAID is looking for collaborations that can co-create and co-design solutions and, where appropriate, co-invest alongside USAID. The intent is to bring together complementary strengths across sectors to move innovations toward accessible prevention options.
What types of partners does USAID expect to see involved?
The description encourages cross-sector collaboration, including public health implementers, product developers, researchers, and private-sector partners who can help translate innovation into practical, accessible prevention tools.
What is the funding instrument type for this opportunity?
The opportunity is listed as an "Other" funding instrument type and described as a discretionary funding category. This reflects the flexible, partnership-oriented nature of the Broad Agency Announcement (BAA) approach.
What is the activity area and CFDA listing?
The activity area is science and technology and other research and development, listed under CFDA 98.001.
Who is eligible to apply?
Eligibility is broad and includes county and local governments, city or township governments, independent school districts, federally recognized Native American tribal governments and other tribal organizations, nonprofits with or without 501(c)(3) status (excluding institutions of higher education in those specific nonprofit categories), individuals, and for-profit organizations other than small businesses.
Are for-profit organizations eligible?
Yes. For-profit organizations other than small businesses are listed as eligible applicants.
Are individuals eligible to apply?
Yes. Individuals are explicitly included in the eligibility list.
Are nonprofit organizations eligible even if they do not have 501(c)(3) status?
Yes. Nonprofits with or without 501(c)(3) status are listed as eligible (with a specific note excluding institutions of higher education in those nonprofit categories).
Are institutions of higher education eligible under the nonprofit categories listed?
The eligibility description specifically notes nonprofits with or without 501(c)(3) status, excluding institutions of higher education in those specific categories. No additional eligibility details are provided here beyond that statement.
What is the funding opportunity number?
The funding opportunity number is "GLOBALHEALTHBAA MICROBICIDES 2021."
What are the key dates mentioned for this opportunity?
The listing includes a creation date of January 25, 2021, and an original closing date of March 11, 2021.
What is the award ceiling?
The stated award ceiling is up to $125,000,000, indicating the potential for large-scale support depending on the scope and structure of the proposed collaboration.
Does the award ceiling mean every award will be $125,000,000?
No specific award size, minimum, or typical award amount is provided in the description. The $125,000,000 figure is presented as a ceiling (maximum), with scale depending on the scope and structure of the collaboration.
What does women-centered choice mean in the context of this opportunity?
Based on the description, women-centered choice refers to HIV prevention products and options that women can control and select themselves, particularly emphasizing the needs of adolescent girls and young women in high-incidence settings.
How does this opportunity support moving products toward real-world use?
The opportunity is meant to support activities beyond early-stage research, including development and testing, piloting and evaluation, and preparation for broader scale-up. USAID also signals interest in solutions that can be manufactured, delivered, and used in resource-limited contexts, which ties R&D to practical implementation considerations.
What is the overall impact USAID is trying to achieve with this call?
The stated intent is to meaningfully reduce HIV infections by accelerating R&D and strengthening the path to rollout of innovative HIV prevention products that women can control, particularly in regions and populations with the highest burden.
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