Opportunity Information: Apply for CDC RFA CK19 1903

The grant opportunity titled "Ecological Surveillance for High-Consequence pathogens in Sierra Leone" (Funding Opportunity Number CDC RFA CK19 1903) is a U.S. Centers for Disease Control and Prevention (CDC) cooperative agreement designed to build and strengthen Sierra Leone's ability to detect and monitor viral hemorrhagic fevers (VHFs) and other high-consequence pathogens before they spread widely in people. The main goal is to improve ecological surveillance within Sierra Leonean public institutions, focusing on the environmental and animal-related factors that can drive disease emergence. By strengthening these upstream surveillance systems, the program aims to support earlier warning, better situational awareness, and more effective prevention strategies to reduce the risk of spillover events from animals or vectors into human populations.

The opportunity emphasizes two major technical priorities. First, it seeks to improve vector surveillance for VHF viruses and other public health threats. Vector surveillance typically means building the capacity to systematically collect, identify, and test organisms such as mosquitoes, ticks, or other arthropods that can carry and transmit pathogens. Strengthening this area supports better mapping of where potential vectors are found, how abundant they are, what pathogens they may be carrying, and how those patterns change over time or across different ecological settings. A stronger vector surveillance system can help public health authorities identify risk hotspots, monitor trends that could signal increased transmission risk, and inform targeted interventions.

Second, the NOFO focuses on improving laboratory capacity to detect VHF viruses and other pathogens of concern in small animals. This component generally relates to building skills, protocols, and infrastructure for safely handling, processing, and testing specimens from small mammals or other wildlife that may serve as reservoirs or incidental hosts for dangerous viruses. Enhancing this laboratory capability supports the detection of pathogens circulating in animal populations, which is often a critical early indicator of potential human risk. When laboratories can reliably identify pathogens in animal samples, it becomes easier to understand what is circulating, where it is circulating, and whether conditions are present for potential spillover into communities.

Structurally, the award is offered as a cooperative agreement, meaning the CDC expects to have substantial involvement in the implementation of the project, often through technical collaboration, joint planning, and ongoing monitoring of progress. The funding falls under the health activity category, with CFDA number 93.318, and is administered by the Department of Health and Human Services through the CDC's National Center for Emerging and Zoonotic Infectious Diseases (NCEZID). The opportunity was published on March 22, 2019, with an original application deadline of May 24, 2019, and required electronic submission by 11:59 p.m. Eastern Time on the due date.

In terms of scale and competitiveness, the NOFO anticipated making a single award (Expected Awards: 1), with an award ceiling of $1,000,000. Eligibility is listed as "Others," with the intent that applicants consult the additional eligibility details referenced in the full announcement. Overall, the program is geared toward building durable, institution-based surveillance and laboratory systems in Sierra Leone that can detect high-risk pathogens earlier, guide prevention efforts more effectively, and ultimately reduce the likelihood that outbreaks of VHFs and similar threats will emerge and spread in the general population.

  • The Department of Health and Human Services, Centers for Disease Control - NCEZID in the health sector is offering a public funding opportunity titled "Ecological Surveillance for High-Consequence pathogens in Sierra Leone" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.318.
  • This funding opportunity was created on Mar 22, 2019.
  • Applicants must submit their applications by May 24, 2019 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $1,000,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for CDC RFA CK19 1903

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Frequently Asked Questions (FAQs)

What is the name of this grant opportunity?

The opportunity is titled "Ecological Surveillance for High-Consequence pathogens in Sierra Leone".

What is the Funding Opportunity Number (NOFO number)?

The Funding Opportunity Number is CDC RFA CK19 1903.

Which U.S. agency is offering this funding?

The funding is offered by the U.S. Centers for Disease Control and Prevention (CDC), within the Department of Health and Human Services (HHS).

Which CDC center administers this opportunity?

The opportunity is administered through CDC's National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).

What type of funding mechanism is this?

This award is a cooperative agreement.

What does it mean that this is a cooperative agreement?

A cooperative agreement indicates CDC expects substantial involvement in the project, which can include technical collaboration, joint planning, and ongoing monitoring of progress during implementation.

What is the overall purpose of this cooperative agreement?

The overall purpose is to build and strengthen Sierra Leone's ability to detect and monitor viral hemorrhagic fevers (VHFs) and other high-consequence pathogens before they spread widely in people, by improving ecological surveillance within Sierra Leonean public institutions.

What does "ecological surveillance" mean in this context?

In this context, ecological surveillance focuses on environmental and animal-related factors that can drive disease emergence, with the goal of identifying risks earlier and improving situational awareness to prevent spillover into humans.

Why does the opportunity focus on "upstream" surveillance?

The opportunity emphasizes upstream surveillance because strengthening early, ecology-linked detection systems can support earlier warning, better situational awareness, and more effective prevention strategies to reduce the risk of animal- or vector-to-human spillover events.

What are the two main technical priorities in this NOFO?

The NOFO emphasizes two major technical priorities:

  1. Improving vector surveillance for VHF viruses and other public health threats.
  2. Improving laboratory capacity to detect VHF viruses and other pathogens of concern in small animals.

What is meant by "vector surveillance" in this opportunity?

Vector surveillance refers to building capacity to systematically collect, identify, and test organisms such as mosquitoes, ticks, or other arthropods that can carry and transmit pathogens.

What outcomes can improved vector surveillance support?

Stronger vector surveillance can help public health authorities:

  • Map where potential vectors are found and how abundant they are
  • Identify what pathogens vectors may be carrying
  • Track how vector and pathogen patterns change over time or across ecological settings
  • Identify risk hotspots and monitor trends that could signal increased transmission risk
  • Inform more targeted interventions

What does the laboratory capacity component focus on?

This component focuses on improving the ability to safely handle, process, and test specimens from small mammals or other wildlife to detect VHF viruses and other pathogens of concern.

Why is detecting pathogens in small animals important for public health?

Detecting pathogens circulating in animal populations can serve as an early indicator of potential human risk. Reliable detection can help clarify what is circulating, where it is circulating, and whether conditions exist for possible spillover into communities.

Where is the program intended to build capacity?

The program is geared toward building durable, institution-based surveillance and laboratory systems within Sierra Leonean public institutions.

What public health threats are specifically mentioned?

The opportunity specifically mentions viral hemorrhagic fevers (VHFs) and also references other high-consequence pathogens and other pathogens of concern.

How many awards did the NOFO anticipate making?

The NOFO anticipated making a single award (Expected Awards: 1).

What is the maximum funding amount (award ceiling)?

The award ceiling is $1,000,000.

What is the activity category for this funding?

The funding falls under the health activity category.

What is the CFDA number associated with this opportunity?

The CFDA number listed is 93.318.

When was the opportunity published?

The opportunity was published on March 22, 2019.

What was the application deadline?

The original application deadline was May 24, 2019.

How were applications required to be submitted?

Applications required electronic submission.

What time zone applied to the submission deadline time?

Electronic submissions were required by 11:59 p.m. Eastern Time on the due date.

Who is eligible to apply?

Eligibility is listed as "Others", and applicants are expected to consult the additional eligibility details referenced in the full announcement.

What is the intended long-term impact of this program?

The program aims to strengthen early detection and prevention so that Sierra Leone can identify high-risk pathogens sooner, guide prevention efforts more effectively, and reduce the likelihood that outbreaks of VHFs and similar threats will emerge and spread in the general population.

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